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An Overview of Levothyroxine Genesis T3+T4

Levothyroxine is a medication used to replace a deficiency of the thyroid hormones T3 and T4 in those with a thyrotoxicosis, which is an overactive thyroid. These hormones influence metabolic rate and protein synthesis, among other functions. A small number of patients with an inborn error of the metabolism of Levothyroxine Genesis T3+T4 may develop symptoms after taking levothyroxine, or ‘Levoxyl’, as the drug is commonly called in the United States. These patients usually have an underactive thyroid (hypothyroidism), and have a genetic mutation that prevents their body from converting T4 into T3. This T3-replacement medication has been known to cause a condition called ‘Levoxidation’, in which the medication is metabolized in the body and causes excess T3 and T4 to be produced. The following is a quick overview of the condition, and what you need to know about Levothyroxine Genesis T3+T4 and the potential for Levoxidation.

What is Levoxyl – Levothyroxine Genesis T3+T4?

Levothyroxine Genesis T3+T4 is a generic version of the brand name ‘Levox’, which is produced and sold by GlaxoSmithKline. Levothyroxine Genesis T3+T4 is indicated for the treatment ofHashimoto’s disease, an autoimmune disorder that affects the thyroid gland. The medication is also used to prevent congenital hypothyroidism and hyperthyroidism. Levoxyl is available as a tablet to take by mouth, with dosage guidelines based on a patient’s age and weight. The drug is given to replace the function of hormones such as TSH, and is taken on a daily basis.

How is Levoxyl given?

Levoxyl Levothyroxine Genesis T3+T4 is usually swallowed whole with water. It can also be mixed with cereal, yogurt or applesauce, and then consumed later in the day. If a patient has trouble swallowing pills whole, a liquid form of the medication is available. The recommended starting dose for patients with hypothyroidism is 1-2 pills per day, and the dosage is increased to 2-4 pills per day once the thyroid health is restored. For patients with hyperthyroidism, the dose is 2-4 pills daily.

What is the risk of Levoxidation?

The risk of a patient developing Levoxidation after starting on Levoxyl Levothyroxine Genesis T3+T4 is very low, and the condition does not occur in everyone taking the medication. The FDA has approved Levoxyl to treat hypothyroidism, and the drug has been on the market for over 50 years, during which time millions of people have taken it. However, there are certain people who are at an increased risk of Levothyroxine Genesis T3+T4 Levoxidation. These include people with: A genetic mutation that prevents the conversion of T4 to T3 A history of ‘hot flashes’, which are feelings of heat in the face and neck An increased rate of metabolism, meaning that the body processes the medication faster than usual A condition called ‘open-angle glaucoma’, in which the pressure inside the eye is higher than normal A history of drug or alcohol abuse A diet that is high in salt or sugar People who are at risk of Levoxidation Levothyroxine Genesis T3+T4 should be aware that the condition exists, and take precautionary steps to avoid it. These steps include:

Genesis T3+T4

Not using the medication for longer than recommended Not exceeding the dosage recommendations Staying hydrated by drinking plenty of water, and avoiding carbonated drinks Avoiding high-salt or high-sugar foods Keeping a close eye on the eye pressure, and immediately contacting a doctor if it rises above normal

How do you know if you’re at risk of Levoxidation?

There is no way to know if you’re at risk of developing Levoxidation, or a condition called ‘autoimmune hypothyroidism’. These are both overactive conditions where the body destroys its own tissues. However, there are some risk factors that can increase the likelihood of developing Levoxidation, even if you don’t have one of the above conditions. These include:

Levothyroxine Genesis T3+T4 Being a woman

Having a family history of hyperthyroidism or thyroid disorders Being over 40 years of age Having high blood pressure Being malnourished These are all factors that can make the body more likely to convert T4 to T3. It is also worth noting that patients who develop autoimmune hypothyroidism after taking Levoxyl have a higher incidence of autoimmune disorders.

How to reduce your risk of Levoxidation

People who are at risk of developing Levoxidation can take steps to reduce their chances of developing the condition. These include: Managing risk factors for the condition, such as keeping the blood pressure in check, and eating a healthy, balanced dietDiscussing any concerns with a doctor before starting Levoxyl, as side effects can occur in some patients Not exceeding the dosage recommendations Staying hydrated by drinking plenty of water, and avoiding carbonated drinks Avoiding high-salt or high-sugar foods Using other medications that are metabolized in the body – Keeping a close eye on the eye pressure, and immediately contacting a doctor if it rises above normal.

Levothyroxine Genesis T3+T4 Conclusion

Levothyroxine Genesis T3+T4 is a medication that is used to treat conditions caused by a deficiency of the thyroid hormones T3 and T4 in the body. It is important to note that it is extremely rare for patients to develop a condition where excess T3 and T4 are produced after starting on the medication. This is described as ‘Levoxidation’, and it is usually associated with an underactive thyroid and is irreversible. There are certain people who are at an increased risk of developing Levoxidation, including people with an autoimmune disorder, an underactive thyroid, or a genetic mutation that prevents the body from converting T4 to T3. It is also worth noting that patients who develop autoimmune hypothyroidism have a higher incidence of autoimmune disorders. If you are at risk of developing Levoxidation Levothyroxine Genesis T3+T4, it is important to discuss the condition with your doctor, and take precautions to reduce your chances of developing it. This includes managing your risk factors, discussing concerns with your doctor, and not taking the medication for longer than recommended.  

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